HP Photosmart C4280 Ink Cartridges

The following 13 products are guaranteed to work in your HP C4280 printer:

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Sets of ink cartridges for HP Photosmart C4280 printer

Genuine High Capacity Black & Tri-Colour HP 350XL / HP 351XL Ink Multi-Pack (HP CB336EE and HP CB338EE)
  • Multipack saving: £3.17

    Compared to buying these separately

  • Pack of 2 high capacity ink cartridges
  • Lowest online price guaranteed

    If within 7 days of buying a product from us, you find the same product cheaper at any other UK online store, we will refund you with 100% of the difference.

  • 12 month guarantee and FREE returns

    If within a year of purchase you happen to experience any quality problem, we'll happily provide a replacement, or a full refund.

    Whatever the reason for returning items to cartridgesave.co.uk, you will never pay a penny for postage.

Best value Genuine

4.3p per page

For most cartridges this is based on 5% coverage on A4 paper. These numbers are based on manufacturer quoted values and are for comparison purposes only.

1,000 pages
580 pages
High Capacity
1 £67.65 (£81.18 inc VAT)
2 £65.98 (£79.18 inc VAT)
3+ £65.33 (£78.40 inc VAT)
Prices includes FREE next-day delivery

Best value Genuine

4.3p per page

For most cartridges this is based on 5% coverage on A4 paper. These numbers are based on manufacturer quoted values and are for comparison purposes only.

1,000 pages
580 pages
£67.65 (£81.18 inc VAT)

FREE next-day delivery

Multi-buy discount
2 £65.98 (£79.18 inc VAT)
3+ £65.33 (£78.40 inc VAT)

Black ink cartridges for HP Photosmart C4280 printer

Colour ink cartridges for HP Photosmart C4280 printer

Customer Questions & Answers

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  • My printer is a Photosmart C4280. I lived in South Africa before moving to the UK. The cartridge numbers I used there were HP 140 and 141. Can I buy these online here?

    HP Photosmart C4280 cartridge numbers

    Unfortunately not, we don't stock the HP 140 / 141 cartridges because they're not the correct cartridge numbers for a Photosmart C4280 (UK printer). Our HP Photosmart C4280 cartridges are only suitable for printers set to the UK zone. Like DVDs, printer cartridges are specific to whichever region you purchased the machine so you must use cartridges with the correct number for your region. However, now that you're living in the UK you may wish for HP to change the region code on your printer so that it can accept the HP 350, 350XL, 351, 351XL cartridges that we stock for the HP Photomsart C4280. Please contact Hewlett Packard directly in order to discuss sourcing the cartridges you need, or resetting the zone on your printer.

    Answered by Nichola Ansbro (Staff Member) - almost 5 years ago
  • Other than the HP Photosmart C4280, what other HP printers use the HP 350 and HP 351 ink cartridges now that I can buy?

    Using Photosmart C4280 ink for other printers

    The best way for you to check which printers the HP 350 and HP 351 ink cartridges are compatible with is to view the product page for our HP 350 and HP 351 multipack (SD412EE). If you click on the link provided and scroll down to he heading, "This item is guaranteed to work in the following printers", this will show you all of the HP printers that can use HP 350 and HP 351 ink cartridges: https://www.cartridgesave.co.uk/SD412EE.html

    Answered by Amanda Garnett (Staff Member) - almost 5 years ago
  • I live in the UK and have an HP Photosmart C4280 All-in-One printer made in the US. If I recall correctly, the power cords (US v UK) are interchangeable as they have a transformer but I'm unsure of what ink to get (I think the HP 350 / 351) and if the ink cartridges made for the UK market will work in the US printer. Can you help? The printer calls for HP 74 / 75 ink.

    Using UK ink in US model HP C4280 printer

    Ink cartridges are numbered specifically for different regions so the cartridge numbers for a US printer will be different to the ones used in the UK. Therefore, unless you ask HP to change the region code on your Photosmart C4280 printer so that it can accept the UK cartridges (HP 350 / 351), then you'll only be able to use the HP 74 / 75 ink cartridges that you've used previously. Please contact HP directly for further assistance: http://www8.hp.com/us/en/contact-hp/ww-contact-us.html

    Answered by Claire Smith (Staff Member) - over 3 years ago
  • I only have a colour ink cartridge in my HP Photosmart C4280 but it's only printing in black and white. How do I print in colour?

    Photosmart C4280 ink replacement

    The HP Photosmart C4280 printer will require that you install two cartridges in order to function properly, both with some remaining ink. You can use one black and one tri-colour cartridge in the Photosmart C4280 for printing everyday text and graphics. You can also install an optional photo colour ink cartridge in the black ink slot to work alongside the tri-colour cartridge when printing colour photos. For black and white photos, you can use the black cartridge alongside the optional photo grey cartridge. Please refer to your HP Photosmart C4280 printer manual for further information on print settings and ink cartridge replacement.

    Answered by Carla McDonald (Staff Member) - over 2 years ago
  • Hi, what's your phone number?

    Ordering Photosmart C4280 ink

    Cartridge Save order line number: 0161 968 5994

    Answered by Joe Hemlin (Staff Member) - over 2 years ago
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Find The Best HP C4280 Ink Cartridges Online

Your HP Photosmart C4280 printer makes great photos, but those great photos drink a lot of printer ink. Have you checked the ink levels on your HP C4280 printer lately? While you probably got a terrific price on it, the day will come when you'll run out of ink. When that happens, you will learn, if you haven't already, just how expensive HP C4280 cartridges are. You have an alternative to high prices and that alternative is Cartridge Save. We sell you your HP Photosmart C4280 ink cartridges, in both colour and black, at shockingly low prices!

Get Your C4280 Ink Delivered For Free

Every HP Photosmart C4280 cartridge we sell at Cartridge Save is fully covered by a no fuss, money back guarantee. We are completely convinced the excellent build quality and spectacular printouts of our HP Photosmart C4280 will win you over, but if they don't, your order is covered by our guarantee. If you are not totally satisfied, you can send your cartridges back to us within 12 months and get your money refunded. You also get free delivery on any C4280 cartridge you buy from us at Cartridge Save!

HP Photosmart C4280 Printer Review

Expert review of the HP Photosmart C4280 printer

Our Verdict:

The HP Photosmart C4280 is a printer which has something of a reputation to live up to. After all, the Photosmart range is synonymous with class these days and the results of the last few models have been worthy of the attention they have garnered. As such, there is a lot of pressure on the HP Photosmart C4280 to succeed where other models have also shone. The big question is, can the HP Photosmart C4280 live up to the hype?


In simple design terms, the HP Photosmart C4280 is every bit as impressive as the previous Photosmart models. This is a printer which boasts a sleek and attractive design and comes in a very subtle, but light cream and white finish. The printer is also a step up from some of the earlier Hewlett-Packard printers which were a little larger than was entirely necessary.


Colour printouts made with the HP Photosmart C4280 are certainly worthy of note. In fact, if you are looking for a printer which produces professional looking photos, then the HP Photosmart C4280 should certainly be on your shopping list. What's more, text documents are clear and crisp to boot, making this a fine all round printer and one which also boasts a very easy to use scanner facility.


There are close to none in truth. In fact, other than the price tag, this is the perfect printer. Shopping around for the best deal on an HP Photosmart C4280 might be handy as they can be fairly expensive to buy, but other than this minor flaw, the HP Photosmart C4280 is a top of the range printer.