HP Photosmart C5280 Ink Cartridges

The following 13 products are guaranteed to work in your HP C5280 printer:

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Sets of ink cartridges for HP Photosmart C5280 printer

Genuine High Capacity Black & Tri-Colour HP 350XL / HP 351XL Ink Multi-Pack (HP CB336EE and HP CB338EE)
  • Multipack saving: £3.25

    Compared to buying these separately

  • Pack of 2 high capacity ink cartridges
  • Lowest online price guaranteed

    If within 7 days of buying a product from us, you find the same product cheaper at any other UK online store, we will refund you with 100% of the difference.

  • 12 month guarantee and FREE returns

    If within a year of purchase you happen to experience any quality problem, we'll happily provide a replacement, or a full refund.

    Whatever the reason for returning items to cartridgesave.co.uk, you will never pay a penny for postage.

Best value Genuine

4.4p per page

For most cartridges this is based on 5% coverage on A4 paper. These numbers are based on manufacturer quoted values and are for comparison purposes only.

1,000 pages
580 pages
High Capacity
1 £69.20 (£83.04 inc VAT)
2 £67.53 (£81.03 inc VAT)
3+ £66.88 (£80.25 inc VAT)
Prices includes FREE next-day delivery

Best value Genuine

4.4p per page

For most cartridges this is based on 5% coverage on A4 paper. These numbers are based on manufacturer quoted values and are for comparison purposes only.

1,000 pages
580 pages
£69.20 (£83.04 inc VAT)

FREE next-day delivery

Multi-buy discount
2 £67.53 (£81.03 inc VAT)
3+ £66.88 (£80.25 inc VAT)

Black ink cartridges for HP Photosmart C5280 printer

Colour ink cartridges for HP Photosmart C5280 printer

Customer Questions & Answers

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Ask us a question we're happy to help!

  • Please could you send me a user manual for the HP Photosmart C5280?

    Photosmart C5280 manual
    Answered by Lindsey Gough (Staff Member) - about 7 years ago
  • How can I get a printhead and what can be the commonest cause of printhead problems with the HP Photosmart C5280 printer?

    HP C5280 printhead

    Unfortunately, we are unable to supply the printhead for this printer. I would recommend contacting HP directly and hopefully they should be able to help further. As we do not sell the printers we are unable to advise on any common faults that occur with particular models.

    Answered by Vicky Lush (Staff Member) - almost 7 years ago
  • Are the 350 / 351 and the 350XL / 351XL cartridges fully compatible? Can I replace the empty 350 and 351 with 350XL and 351XL?

    HP Photosmart C5280 replacement ink cartridges

    Yes, the HP Photosmart C5280 can use any combination of these cartridges, provided that you have one black and one colour cartridge installed. The XL cartridges are simply a higher capacity version of the 350 and 351 and should work in the same way. The only difference being that they have more ink inside and will last longer.

    Answered by Claire Smith (Staff Member) - about 6 years ago
  • Can I feel confident if I buy the alternative to the genuine HP C5280 replacement cartidge? What is the downside, if any?

    Buying compatible Photosmart C5280 ink

    There's very little difference between the performance of our compatible HP Photosmart C5280 ink cartridges and the HP original ink cartridges. Our compatible HP C5280 ink cartridges are strictly checked and tested to ensure that they produce high quality prints and they're fitted with the correct chip so they can be installed directly into your printer without any problems. In the unlikely event that you're ever unsatisfied with the quality or reliability of our compatible Photosmart C5280 ink then we'll give you a full refund. An occasional downside of using any compatible ink cartridge can be that they don't always report the ink levels accurately but this shouldn't affect your printing or your ability to use up all the ink within the cartridge, you should ignore any low ink warnings and print until the cartridge runs out.

    Answered by Stacy Bass (Staff Member) - over 5 years ago
  • How do I change the Photosmart C5280 cartridges?

    Replacing HP C5280 ink cartridges

    Please refer to your HP Photosmart C5280 printer manual for instructions on how to change the ink cartridges. The Photosmart C5280 printer manual is available for download on the HP website if you don't have a copy: http://h10025.www1.hp.com/ewfrf/wc/manualCategory?cc=uk&dlc=en&lc=en&product=3204464&

    Answered by Amanda Garnett (Staff Member) - over 4 years ago
  • Do you supply replacement colour ink cartridges with the code 351 for a HP C5280 printer?

    Replacement HP C5280 colour ink cartridge

    Yes, we currently stock the genuine HP 351 colour ink cartridge, the genuine HP 351XL colour ink cartridge and the compatible HP 351XL colour ink cartridge which can all be used in the colour cartridge slot within your HP Photosmart C5280 printer. All of these cartridges are shown above, simply click "Add to basket" next to whichever cartridge you require to place an order.

    Answered by Tamara Sawyer (Staff Member) - almost 4 years ago
  • I've got a Photosmart C5280 printer but l can't get the cartridges in South Africa with numbers 350 and 351. I wanted to know if there are any other different cartridge numbers which l can use? Regards, Noel.

    HP Photosmart C5280 cartridge numbers

    It depends on where you purchased your HP Photosmart C5280 printer as to which cartridge numbers it can accept. Like DVDs, ink cartridges are specific to the region in which the machine was purchased. For UK bought HP C5280 Photosmart printers you need to use HP 350, HP 350XL, HP 351, HP 351XL, HP 348 or HP 100 cartridges as listed on our website. The cartridge numbers used in South Afric are different so you'll need to contact HP to find out which numbers are used in this region if you bought the printer over there. If your HP Photosmart C5280 printer was purchased in the UK and you've moved to South Africa and are now stuggling to buy the correct cartridge numbers (HP 350 / 351) then we advise you to contact HP directly so they can change the region code on your printer so that it will accept the cartridge being sold in your region as we only deliver within the UK.

    Answered by Carla McDonald (Staff Member) - about 3 years ago
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Save Money and Buy Cheap HP Photosmart C5280 Ink Online

The HP Photosmart C5280 offers vibrant colour photo printing but to get the best pictures every time you print requires using original HP Vivera inks which can be costly. That is until you shop at Cartridge Save where we pride ourselves in providing discount prices in comparison to the inflated high street prices or other online stores. We stock cheap HP C5280 ink cartridges to cover all your printing needs, so whether you require black HP ink to print crisp text documents or a tri-colour cartridge for full colour photos, our fantastic range is available to ensure that high prices are a thing of the past.

Order Photosmart C5280 Cartridges With Speedy Delivery

It can be a time-consuming process to work out which cartridges fit your printer and where to buy them at reasonable prices. Here at Cartridge Save we do the hard work so you get the correct cartridges for your printer delivered FREE of charge with expected arrival the following day. Our no quibbles money back guarantee ensures that all HP Photosmart C5280 inks are compatible with the printers we specify and we are also confident that the build quality of our cartridges will mean you avoid incidents of faulty cartridges. If for any reason you do want to claim a refund please call our friendly support team within 12 months who are happy to help. Buying your HP C5280 ink just became more reliable and a great deal easier thanks to Cartridge Save.

HP Photosmart C5280 Printer Review

Expert review of the HP Photosmart C5280 printer

Our Verdict:

The HP C5280 is a versatile, multifunction printer that can handle a range of media from plain paper and card to a CD or DVD and labels. The C5280 inkjet printer accepts most major memory cards, allowing you to print directly. Unfortunately, the lack of PictBridge support and only a single USB PC connection does bring it down and could pose problems for both home and office users.


The stylish C5280 has a 6 cm colour LDC display and a functional 11 button control panel that provides access to a variety of print functions and even allows the end user to print directly from a memory card. The paper feed system is similar to other HP all-in-ones with its front loading input tray, capable of holding 125 sheets. There's also a CD or DVD disk tray for direct printing.


For an entry-level all-in-one, the C5280 has a lot of things going for it. It's rammed full of features and has a great spec when you compare to similar devices on the market. Quoted print speeds of 32 ppm and 24 ppm for mono and colour draft are a tad farfetched, expect nearer to 12 and 10 for normal quality which, for a home device, is pretty nippy.


The print quality of the C5280 is disappointing especially when it comes to text documents. Characters appear fuzzy with signs of fading; this only gets worse when using the copier. Photographs also cause the HP C5280 inkjet printer problems, especially when printing in draft or normal mode. HP needs to also look at USB and PictBridge support if it wants the C5280 to be a versatile home device.